Top 100 2025
Company
TOLREMO therapeutics AG
Incorporated
March 2017
Headquarter
Basel
Support
Biotech Biotech Cancer Drug development platforms Drug discovery Screening Small molecule drugs

Development of resistance-breaking cancer therapies

TOLREMO therapeutics' mission is to prevent non-genetic cancer drug resistance by dismantling the earliest defense to targeted therapies. Led by phenotypic insights, we discovered a pivotal mechanism that governs critical transcriptional resistance pathways. Our clinical compound TT125-802 is an orally available small molecule inhibitor designed to block these survival techniques to significantly improve the response rates and durability of established treatments.

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