Top100 Hall of Fame

The Hall of Fame honors Swiss startups that have achieved the “Magic 100”: They have raised at least CHF 100 million, or generated CHF 100 million in revenue, or been acquired for over CHF 100 million. These startups are global industry leaders, innovation drivers, and role models for the next generation of entrepreneurs.

From Startup to Global Champions

These trailblazers have scaled beyond expectations—becoming industry leaders, job creators, and global ambassadors of Swiss excellence. Their journeys reflect the power of vision, resilience, and innovation. Discover the startups that are transforming industries and inspiring the world shapers of tomorrow.

Zurich Instruments AG

Instruments for dynamic signal analysis

EraCal Therapeutics AG

We develop the next generation anti-obesity drug

Crispr Therapeutics AG

Developing cures for serious human genetic diseases

Climeworks AG

Capturing CO2 from air

Coople (Schweiz) AG

Digital staffing agency for short-term assignments

Bright Peak Therapeutics AG

Next-generation engineered cytokines

Araris Biotech AG

Building tomorrow's antibody-drug conjugates (ADCs)

Numab Therapeutics AG

Innovates and develops antibody-based therapeutics

Sophia Genetics SA

Democratizing Data-Driven Medicine

Sygnum Bank AG

Digital asset specialist with global reach

ONWARD Medical SA

Enabling nervous system rewiring

Xeltis AG

Bioabsorbable synthetic heart valves and vascular grafts

Virtamed AG

Simulators for medical training and education

HAYA Therapeutics SA

Treating heart failure through innovative RNA-therapies

Kandou Bus SA

Low power consumption chip connections

Ecorobotix SA

Innovative solutions for sustainable agriculture

Alentis Therapeutics AG

Developing Claudin-1 antibodies for cancer and fibrosis

GetYourGuide AG

Booking website for tours and activities

Covagen AG (acquired by Johnson & Johnson)

Creating the next generation of biologics

Beekeeper AG

Empowering entire workforces

GlycoEra AG

Glycobiology and protein degradation

Amal Therapeutics SA

Cancer vaccines

Planted Foods AG

Planted meats

ServiceHunter AG (quitt.)

Easily register and administrate your domestic help.

Nexxiot AG

enabler of the digitized supply chain

Oculis SA

Next Generation of Topical Ophthalmic Treatments

NBE-Therapeutics LLC

Antibody-based NBEs

Versantis AG

Conquer liver diseases and saves lives

Anaveon AG

Immunotherapies for cancer

bexio AG

Business software for SMEs

Energy Vault SA

Concrete energy storage technology

Optotune AG

Inexpensive, scalable, precisely focus tunable lenses based

SWISSto12 SA

Agile space technology to connect the world

T3 Pharmaceuticals AG

Developing the next generation bacterial cancer therapy

ANYbotics AG

Autonomous robots for industrial inspection

Biocartis SA

Molecular diagnostics platform

Distalmotion SA

Making Sense of Robotic Surgery

VIU VENTURES AG

Challenging the established rules in the eyewear industry

Smallpdf GmbH

Online tools to edit PDFs

MindMaze SA

Bringing real emotion to virtual reality

Frontify AG

The platform for building powerful brand experience

On AG

Introducing zero-gravity running

BioVersys AG

Saving lives in resistant times.

Alpian

Innovative Wealth Management

Scandit AG

Smart Data Capture

Yokoy Group AG

Your expenses and company credit cards on autopilot

Lunaphore Technologies SA

Tumor analysis platform

Redbiotec AG

Therapeutic bacteria for treating cancer & genetic disorders

Anokion SA

Promoting IMMUNE TOLERANCE, ameliorating disease

Proton SA

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